2，5-diamino-4,6-dichloropyrimidine合成路线
一、 产品特点：
结构式：
NClClNN
N CAS: 55583-59-0
Mp: 260-261[H2O]; 198[Ethanol]; 185-187[water/ethanol]
二、 合成路线分析
1、路线1
ONONOAONONOONOBClNClNOONClClNH2ClCNClNDTM
67-52-7 480-68-2 4359-87-9 91322-00-8 StepA: J.O.C 67.22.2002.7833-38;
T .L. 41.12.2000.2011-14 StepB/C/D J.O.C 19.1954.930-32
2、路线2
OOOAOONOOOOBONOOO
6829-40-9
O6829-41-0
OONOO+NNNCNNNNODTM
6829-40-9 50-01-1 56830-58-1
Step A: J.Hetercyclo.Chem.41.5.2004.777-782; Tetrahedr 61.49.2005.11577-600 J.O.C 50.26.1985.5598-604; Synthesis Commun 32.7.2002.1031-40 J.O.C 18.1992.4820-28 J.A.C.S 114.15.1992 6227-38
J.Hetercyclo. Chem 24.1987.1573-79 J. Biol.Chem 130.1939.347 Step B Tetrehydr 61.49.2005.11577-600; J.O.C 50.26.1985.5598-5604 J.O.C 52.18.1987.3986-93 J.O.C 57.18.1992.4820-28 Org.Syn 40.1960.24 J.A.C.S 66.1944.350
Step C: Step D:
3、路线3
Org.Lett 5.22.2003.4187-90; T.L 23.37.1982.3835-36 Synthesis 7.1990.587-5 Synthesis 7.1990.587-5 J.O.C 40.1975.3141-3142 J.O.C 44.1979.4836-41
